This study investigates the synthesis of mPEG-PLA diblock copolymers through a controlled ring-opening polymerization. Various reaction conditions, including temperature, were adjusted to achieve desired molecular weights and polydispersity indices. The resulting copolymers were analyzed using techniques such as high-performance liquid chromatograp

Poly(lactic acid) PLA (PLA) is a versatile biocompatible polymer widely used in drug delivery systems. However, its rapid degradation and poor water solubility limit its efficacy. To overcome these challenges, PEGylation, the process of attaching polyethylene glycol PEG, has emerged as a promising strategy. Biocompatible PEGylation enhances PLA's d